Abstract Background Physical protein-protein interaction (PPI) is a critical phenomenon for the function of most proteins in living organisms and a significant fraction of PPIs are the result of domain-domain interactions. Exon shuffling. intron-mediated recombination of exons from existing genes. is known to have been a major mechanism of domain shuffling in metazoans. https://ashleyshomestores.shop/product-category/true-convection-range/